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Sometimes they have both depressionand cognitive impairment. The difference between conscious sedation andanaesthesia is one of degree. 2006; Hutchison andBignall 2008; Jobe and Ikegami 1998).

It avoids the complications associated with bloodproducts and is useful for treating bleeding episodes in mild hemophilia and as prophylaxis beforeminor surgery. However,dominant oncogenic p53 proteins actively drive metastasis by promoting angio-genesis through upregulating the expression of chemokines and other angiogenicfactors in tumor cells.

Seniors have often heard their physiciansurging them to get enough folate through healthy diet and daily supple-ments.

Despite widespread professional accept-ance of ECT, service-user groups have often opposed its use. It is defined as theabsolute difference in incidence measures for the outcomeof interest between those with exposure and those withoutexposure to the risk factor of interest (Table 21.1)

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Those haloge-nated solvents that produce selective and potent nephrotoxi-city have some features in common (Figure 7.7): (i) thenephrotoxicity is dependent on conjugation with glutathione(GSH); (ii) further metabolism to the cysteine conjugategenerates the penultimate, nephrotoxic species; and (iii) theportion of the cysteine conjugate derived from the parentmolecule provides a good leaving group for the subsequentreaction that generates the ultimate, nephrotoxic metabolite.GSH is an important component of cellular antioxidantdefense and is typically considered protective againstmost cytotoxic chemicals (e.g., see discussion later aboutApAp). The thinner it is rolled out, the crunchier the crackerwill be

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The villi adjacentto the decidua basalis rapidly increase in size and number andbecome highly branched. Antioxidative enzymes in human nasalmucosa after exposure to ozone

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